• Bioeconomy
  • Chemistry and Materials
  • Energy and Environment

Advanced High-Throughput Technologies Platform for Biorefineries Catalysts Design (REALCAT)



We are a high-throughput screening platform, unique in the world, dedicated to catalysis in all its forms, i.e. biocatalysis (enzymes and fermentation), chemical catalysis (homogeneous and heterogeneous) as well as their new combinations (hybrid catalysis). With its extraordinary potential, our platform is a major player in all fields related to catalysis, such as the environment, energy, health and nutrition. We are open to all academic and industrial collaborations and propose services in line with our expertise.


  • Sébastien Paul
  • Svetlana Heyte
    Technical manager


Avenue Paul Langevin
Campus Cité scientifique, Centrale Lille


Advanced High-Throughput Technologies Platform for Biorefineries Catalysts Design

Chiffres clés

• 80 publications over 5 years
• 6 patents
• More than 50 projects per year (national and international)
• More than 20 industrial partners
• More than 25 visits per year
• Participation in the training of nearly 150 students


Effectif total : 4



• Catalytic systems (synthesis, characterization and testing)
• Catalytic materials
• Biocatalysis and chemical catalysis
• Hybrid catalysis
• Catalysts
• Biorefinery
• Development of catalysts in all its forms
• Combination of catalysts
• Characterization and high throughput evaluation of catalysts

Example(s) of projects

• Study of catalysts for the ammoxidation of glycerol into acrylonitrile
• Optimization of lipid production process in microfermentation

Collaborations/Partners/Scientific clients

ISARA Lyon, ESA Angers, INP Purpan, INRA Avignon ,INRA Rennes, ISV Bordeaux, UMR Agroécologie Dijon, Arvalis-Institut du Végétal, Chambre d’Agriculture du Nord-Pas de Calais, Institut Technique de la Betterave, FREDON Nord-Pas de Calais, Pôle Légumes Région Nord, CRRG, Dijon Céréales , Bureau Interprofessionnel des Vins de Bourgogne, In Vivo, CETAC et GIE Club 5 (sélectionneurs de blé), , Faculté des sciences Biologie et Institut Petrou Poli chimie macromoléculaire, , Université de Strasbourg, ANSES, Civil Engineering Department of Ecole Centrale de Lille, U Inserm 995, UDR ABI, CHR de Lille, Génoscope D’Evry, Université de Lille, Université de Marseille, Université de Strastbourg, Université de Clermont-Auvergne, Université de Reims Champagne-Ardenne (URCA), UPJV Amiens, Université La Salle Beauvais, HEI Lille, , Institut des Sciences Chimiques de Rennes

Gembloux Agro-BioTech-Université de Liège (Belgium), Université de Gand (Belgium), Université Catholique de Louvain-la-Neuve (Belgium), Université Catholique de Louvain (Belgium), Plateformes européennes de criblage de catalyseurs biologique (TU Berlin, Université de Darmstadt, Université de Greifswald, Genome foundry en UK, etc.), Université de Sant Paulo (Brazil), Université de Ouagadougou (Burkina Faso), Catalysis Research Center de Sapporo (Japan), Université de MALAGA (Spain), Université Blida 1 (Algeria), Université de bologne (Italy), Institut ETH de Zurich (Switzerland), Materianova (Belgium), Centre Wallon de Recherches Agronomiques (Belgium), Provinciaal Proefcentrumvoorde Groenteteelt (Belgium), Inagro (Belgium), Institut National Agronomique de Tunis (Tunisia), INRA de Meknès (Morocco), INRA de Rabat (Morocco), Institut Agronomique et Vétérinaire Hassan II de Rabat (Morocco), Université de Padova (Italy), , Université d’Iquitos (Peru), School of Pharmacy of London (Angleterre), Université de Bari (Italy), Université d’Antananarivo (Madagascar), Centre de Biotechnologie de Borj Cédria (Tunisia), Université Nangui Abrogoua (Ivory Coast), Université des Frères Mentouri (Algeria), Gand (Belgium), Iasi (Romania)

Collaborations/Partners/Private Clients

Adisseo, Ingredia, Solvay, Total, Weylchem ...

Services offers

Applications sectors

  • Biotechnology
  • Energy
  • Agri-food industry
  • Chemistry / Plastics (Glue, Plastic, Rubber...)
  • Materials (Metal, Glass, Ceramic, Composite...)
  • Cosmetics
  • Science / Research

Services provided

• Performance evaluation of chemical (homogeneous or heterogeneous) and biological (enzymes and fermentations) catalysts using high throughput automated systems
• Synthesis of chemical (homogeneous and heterogeneous) and biological (recombinant enzymes and new microbial strains) catalysts at high throughput
• Structural characterization and elemental analysis of chemical and biological materials (catalysts, reaction products, metabolites, etc.) at high throughput
• Transfer to high throughput of current activities performed at low throughput in chemistry and biology laboratories (synthesis of catalysts, calcination, cell culture, measurement of antimicrobial activities, proteomics, etc.)

Training offers

Training in equipment, analysis tools and methods

Consulting services

We provide consulting services related to all our areas of expertise.


The REALCAT platform includes:
• A centralized server for automated data collection and intelligent processing using an integrated LIMS system
• Robots for automated synthesis of chemical catalysts, new biocatalysts and hybrid catalysts
• A complete range of high throughput chemical characterization tools
• Numerous tools for the evaluation of the catalytic performance of catalysts, including a series of versatile continuous and parallel batch reactors/fermenters - for gas-phase, liquid-phase or multiphase reactions - combined with ultra-fast on-line analytical tools

See the detailed list of equipment: http://www.realcat.fr/fr/realcat-techniques-Equipements.html


Nom Modèle Marque
MALDI TOF/TOF mass spectrometer Autoflex Speed/ Bruker
Liquid chromatography with mass spectrometer UPLC-Q-TOF-IMS Acquity UPLC Synapt G2-Si HDMS / Waters
Spectrophotometer UV-Vis Cary 3500 / Agilent
Multi-well plate microfermenter BioLector/ M2PLabs
Colony picker QPix 460 / Molecular Devices
Automated pipetting platform Biomek NXp/ Beckman Coulter
Robotic platform for catalyst synthesis and testing Catimpreg/ Chemspeed
Robotic platform for catalyst synthesis and testing Autoplant/ Chemspeed
X-ray diffractometer D8 Discover/ Bruker
Catalyst test system Flowrence/ Avantium


Affiliated institutions / organisations

Centrale Lille

Unit(s) of attachment


Competitive cluster


Regional strategic areas of activity

  • Bioeconomy
  • Chemistry and Materials
    • Industrial processes engineering, efficient processes
  • Energy and Environment