• Bioeconomy
  • Chemistry and Materials

Enzymatic and Cellular Engineering (GEC)

Research unit - UMR-CNRS 7025


The research conducted within the GEC is based on the premise that solutions to major scientific challenges are found in nature. They combine three approaches: the use of bioresources, bioinspiration and biomimicry.
With its internationally recognized expertise in biotechnology, the GEC unit develops various models of varying levels of complexity, to explain the dynamics of biological phenomena and to propose innovative solutions to scientific and societal problems.
The activities of the GEC are thus naturally linked between the exploitation of bioresources and plant metabolism and the creation of bioinspired materials or molecular mimes for recognition.


  • Karsten Haupt


Rue du docteur Schweitzer



Effectif total : 37

Personnel de recherche : 24

Personnel d'appui à la recherche : 13



• Biotechnology
• Biomimetics
• Plant metabolism
• Biolubricants
• Biofuels
• Antioxidants
• Anticancer
• Antimicrobials
• Antifungals
• Antibiotic resistance
• Study of pathogenic host relationship mechanisms

Example(s) of projects

• FuturoLeaf: develops a bio-inspired SSCF technology based on the hierarchical and porous 3D assemblies of nanocellulosic materials capturing water and transporting gases and nutrients for the photosynthetic microbial cells

• SAMOSS: Improving the development of biosensors in combination with optochemical detection techniques in application areas and through wider dissemination of knowledge

• EraDic: Develop a predictive tool for recurrence in patients with chronic myeloid leukemia after cessation of conventional treatment with first- and second-generation kinase inhibitors

• COALA: elucidate the antifungal mode of action of amphiphilic lipid compounds on rapeseed pathogens.

• XYLESA: isolate specific peptide ligands of lipase secreted in the establishment of diseases associated with Xylella fastidiosa, capable of recognizing it for diagnostic applications and inhibiting its enzymatic activity for phytosanitary applications.

• ANOI aims to determine the identification and classification of oilseed plants of interest and to improve the productivity of oilseed crops of four model plants.

Example(s) of publications

1. Raquel Martins-Noguerol, Sebastien Acket, Manuel Adrián Troncoso-Ponce, Rafael Garcés, Mónica Venegas-Calerón et al. Characterization and impact of sunflower plastidial octanoyltransferases (Helianthus annuus L.) on oil composition
Journal of Plant Physiology, Elsevier, 2022, 274, pp.153730. 🡭

2. Sivanandam Veeramuthu Natarajan, Nicola D’amelio, Victor Muñoz. NMR Relaxation Dispersion Methods for the Structural and Dynamic Analysis of Quickly Interconverting, Low-Populated Conformational Substates Protein Folding, 2376, Springer US, pp.187-203, 2022, Methods in Molecular Biology, 🡭

3.Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou et al. Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease
Journal of the American Society of Nephrology, American Society of Nephrology, 2022, 🡭

4. Juan Carlos Rubio-Gutierrez, Pablo Mendez-Hernández, yann Guéguen, Pierre Galichon, Marcela Tamayo-Ortiz et al. Overview of Traditional and Environmental Factors Related to Bone Health Environmental Science and Pollution Research, Springer Verlag. 🡭

5. Nébéwia Griffete, Laurent Michot, Carlo Gonzato. An easy synthesis of small, stable and water-compatible superparamagnetic protein-specific molecularly imprinted nanoparticles Polymer, Elsevier, 2022, 239, pp.124446. 🡭

All our publications can be found here : 🡭

Collaborations/Partners/Scientific clients

Université Picardie Jules Verne, Sorbonne Université, INSERM, Université de Paris, Université de Reims Champagne-Ardenne, Institut Pasteur, Russian Academy Of Scinces, Université de Lille, Université de Laval, VTT Technical Research Centre of Finland Ltd

Collaborations/Partners/Private Clients


Services offers

Applications sectors

  • Biotechnology
  • Health / wellness
  • Agriculture
  • Education / Training
  • Cosmetics
  • Science / Research

Services provided

We provide services on all our skills

Training offers

We provide training on all our skills

Consulting services

We provide consulting services on all our skills


Biocatalysis, implementation of enzymes in unconventional environments: reactors, identification and quantification, kinetic monitoring, HPLC fleet.

Biophysical characterization of biomolecules, self-assembly of amphiphilic molecules, biomimetic membranes: liquid and solid NMR, Diffusion of laser beam, molecular dynamics simulations, peptide webserver.

Fermentation: batch and reactors

Discover the detailed equipment list: 🡭


Affiliated institutions / organisations

Regional strategic areas of activity

  • Bioeconomy
    • Biobased chemistry
    • Processes applied to the bioeconomy
  • Chemistry and Materials
    • Industrial processes engineering, efficient processes
    • Recycling of materials and efficient use of material resources
    • Textiles, composites, materials