• Health and Nutrition

Genomics platform (GO@L)



Our platform provides a wide range of solutions and expertise in the field of medium/high throughput genomics. It includes two specialized hubs: the "Functional and Structural Genomics" hub, which develops its expertise in particular for translational research on cancer, and the "Transcriptomics & Applied Genomics" (TAG) hub, specialized in microbiology applications. With a global or targeted approach, we ensure the follow-up and the realization of research projects from the qualification of samples, the preparation of libraries and their sequencing, to the bioinformatics and biostatistical analysis of these data. We are open to all academic and industrial collaborations and propose training and services in line with our expertise.


  • Martin Figeac
    Technical manager
  • David Hot
    Scientific manager


Bâtiment C9, Avenue Mendeleiev
Campus Cité scientifique, Université de Lille


Chiffres clés

• 28 projects carried out over 2019-2020 (for 52 submitted)
• 90% of projects at regional level, 5% at national level and 5% at European level
• 24 publications on 2019-2020 (including 2 as project manager)
• 23% of the activity in technology watch


Effectif total : 10



• “Whole genome” genomics: WGS, WES, amplicon-seq, Tn-seq, CGH-arrays, single-cell
• Transcriptomics: RNA-seq, sRNA-seq, dRNA-seq, NGS-RACE, qRT-PCR, RNA-seq full-length, micro-arrays, DGE, single-cell
• Metagenomics: targeted amplicon-seq 16S-ITS
• Whole genome sequencing and resequencing (human, bacteria, virus)
• Whole Exome Sequencing (WES) of diverse qualities
• Targeted sequencing
• 16S metagenomics
• RNA-seq (DGE) and scRNA-seq
• Microarrays and Nanostring DGE

Example(s) of projects

• Metabolic disturbances induced by smoking, role of the microbiota
• Study of clinical and molecular features associated with Met exon 14 splice site mutations in lung cancer
• Search for differential transcriptomic profiles (mRNA, miRNA, lncRNA...) related to socioeconomic environment in women with high grade serous ovarian cancer
• Use of Flagellin as an adjunct in the antibiotic treatment of bacterial pneumopathies

Collaborations/Partners/Scientific clients

Institut Pasteur de Lille, CNRS, CHU de Lille, CHU de Rouen, ANSES, BIOTICLA, IAB

Collaborations/Partners/Private Clients

OCR, Gènes Diffusion

Services offers

Applications sectors

  • Health / wellness
  • Science / Research

Services provided

• Expertise in feasibility study and in setting up genomic analysis projects for medium / high throughput projects
• Sequencing technology in line with the project, its complexity and depending on the type of samples
• Follow-up and implementation of research projects from sample qualification, preparation of libraries and their sequencing, to bioinformatics and biostatistical analysis of these data

From the realization of the experiments to the support of the teams, the platform brings its expertise on the processing of the generated data:
• Genomic assembly, characterization and annotation, variant detection and annotation, study of Mendelian transmission
• Differential expression analysis, unsupervised analysis
• Taxonomic assignment, diversity assessment (α and β), dysbiosis measurement

Consulting services

We provide consulting services related to all our areas of expertise.


We possess a wide range of equipment:
• Sequencers for WGS and RNA-seq in short and long reads
• Microarrays for DGE (Differential Gene Expression)
• Equipment for scRNA-seq and scDNA-seq
• Computer servers/clusters for analysis and development of bioinformatics tools


Nom Modèle Marque
Short reads WGS and RNA-seq MiSeq/ Illumina
Long reads sequencing device MinIon/ Oxford Nanopore Technologies
Ion Torrent Sequencer PGM/ Thermo Fisher Scientific
Ion Torrent Sequencer S5/ Thermo Fisher Scientific
DNA microarray for DGE Agilent Technologies
Nanostring nCounter Nanostring
Chromium Single Cell pour le scRNA-seq 10x genomics
Tapestri multi-omics platform for scDNA-seq Mission Bio


Affiliated institutions / organisations

CHU de Lille

Unit(s) of attachment



Regional strategic areas of activity

  • Health and Nutrition
    • Food ingredients
    • Medicine of the future: new health equipment and e-health
    • Safe, healthy and sustainable food