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Health and Nutrition
Lille In vivo Imaging and Functional Exploration (LIIFE)
Platform
Our platform brings together resources and expertise in in-vivo imaging in humans and rodents, and in behavioral analysis of rodents. We offer tools for the cross-sectional study of a wide range of pathologies, particularly in neurological and psychiatric diseases. We propose both harmonization of advanced MRI sequences between the Rodent and Human platforms, as well as signal analysis methods, allowing users to benefit from advanced techniques, such as brain connectivity analysis, morphometry, magnetic susceptibility quantification, automatic segmentation tools, as well as artificial intelligence techniques. We are open to academic and industrial collaborations.
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Renaud Lopes
Technical manager -
Jean-Pierre Pruvo
1 place de Verdun
Faculté de médecine, Pôle recherche
59000 LILLE
https://ums-plbs.univ-lille.fr/les-plateformes-constitutives/imagerie-du-vivant-et-fonctions
Chiffres clés
• 80 projects / year, including 15 industrial• 30 users / year
• 2 500 imaging exams performed / year
• 20 publications / year
Effectif
Effectif total : 21
Skills
• Behavioral and functional analysis
• MRI imaging
• Morphological exploration of organs by MRI
• Evaluation of rodent physiopathological models
• Brain connectivity
• Morphometry
• Magnetic susceptibility
• Artificial intelligence
• Data processing and computer tools related to imaging
Example(s) of projects
Collaborations/Partners/Scientific clients
Collaborations/Partners/Private Clients
Applications sectors
- Biotechnology
- Health / wellness
- Science / Research
Services provided
• Quantification of biological phenomena by relaxometry, diffusion and MR spectroscopy
• Morphological exploration of organs by MRI
• Data processing and development of IT tools related to preclinical medical imaging
Human platform
• Highlighting the structural organization of the brain:
- volume and surface analysis, morphometry
- mapping of diffusion/tractography imaging
- perfusion imaging
• Extraction of functional organization:
- task-specific activation
- brain at rest: brain networks, functional connectome
• Statistical analysis, data processing and development of computer tools (statistics, signal processing or artificial intelligence) related to imaging
Consulting services
• 7T MRI (Diffusion tensor, ASL and T1 perfusion, T1 and T2 relaxometry...)
• a small animal micro-PET-CT that offers the possibility to perform PET imaging coupled with CT in rodents using a fluorinated radiotracer (FDG, FDOPA)
• behavioural and functional exploration platform, allowing the evaluation of rodent pathophysiological models for cognitive abilities, motor disorders, and anxiety/depression traits
• 3T MRI dedicated to the research in the Lille University Hospital
• 128 channel EGI's MR-compatible EEG Systems
• ESys fMRI System with complex experimental paradigm in functional imaging
• Cluster 176 CPU Cores 470 Gb RAM that supports the entire imaging data analysis computation in an optimal way
See the detailed list of equipment here: http://www.ci2c.fr/facilities_precli.php
Equipments
| Nom | Modèle | Marque |
|---|---|---|
| Micro MRI 7T rodent | ||
| MRI 0.2T large mammal | Hitachi medical systems | |
| MRI 3T clinical research | ||
| 128 channel EGI's MR-compatible EEG Systems | ||
| ESys fMRI System | ||
| Wireless EEG system for mouse | ||
| Behavioral test arenas | ||
| MicroPET-CT Rodent |
Affiliated institutions / organisations
Unit(s) of attachment
Groups/Networks/Federations
Labellisations
Regional strategic areas of activity
- Health and Nutrition