Simplifying Care of Complex Surgical Patients (SSPC)

Contact name	Email	phone number
PECOURT Elodie	elodie.pecourt@u-picardie.fr	(+33) 3 22 82 74 55
REGIMBEAU Jean-Marc	regimbeau.jean-marc@chu-amiens.fr

https://www.u-picardie.fr/unites-de-recherche/sspc/presentation/

1 Rond Point du Professeur Christian Cabrol
Service de chirurgie digestive
80054 AMIENS CEDEX 1

The work of the SSPC research unit is based on two central questions: • What is a complex patient? For the unit, a complex patient is defined as follows: • A patient for whom the processes related to care cannot be either routine or standard (HAS) • Patient requiring major surgery (lung resection) • Patient operated in emergency • Patient with underlying disease (age, ASA III....) • Patient with a socio-economic and socio-cultural environment (deprivation) • Patient with a post-operative complication • What is enhanced rehabilitation after surgery (ARS)? It is a set of pre-, intra- and post-operative measures aimed at reducing post-operative complications and therefore the length of stay of patients.

Nombre de chercheurs : 24
Nombre de doctorants :
Nombre de personnel d'appui à la recherche :
Effectif total : 27

1. PHRC National ABAP project "Interest of postoperative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis" This study evaluates the interest of postoperative antibiotic therapy after laparoscopic appendectomy for complicated forms of acute appendicitis (excluding generalized peritonitis). Prospective, randomised phase III study against placebo National PHRC 2016 to the tune of €890,204 Project sponsor: Digestive Surgery Department of the Amiens-Picardy University Hospital. 2. PHRC National CASPER project "Prospective multicenter double-blind study comparing Caspofungin to placebo for the treatment of ICU yeast intra-abdominal infection" This study will evaluate whether antifungal treatment with Caspofungin, compared to placebo, increases survival in severe patients hospitalised in intensive care units for intra-abdominal candidiasis. Prospective, double-blind, placebo-controlled study National PHRC 2017 with a budget of €1,205,260 Sponsor: Anesthesia-Resuscitation Department of the Amiens-Picardy University Hospital (CHU)

1 - Sabbagh, C ; Bar, S ; Regimbeau, JM , Comment on: Predictors of failure to reach target sample size in surgical randomized trials., Br J Surg, 2022, 2 - Genser, L ; Lim, C ; Barbier, L ; Regimbeau, JM ; Hobeika, C ; Goumard, C & al , Assessment of Factors Associated with Morbidity and Textbook Outcomes of Laparoscopic Liver Resection in Obese Patients: A French Nationwide Study., J Am Coll Surg, 2022, 3 - Dupont, H ; Malaquin, S ; Villeret, L ; Macq, PY ; Ammenouche, N ; Tinturier, F & al , Is ß-d-glucan Relevant for the Diagnosis and Follow-Up of Intensive Care Patients with Yeast-Complicated Intra-Abdominal Infection?, J Fungi (Basel), 2022, 8, 4 - Roger, C ; Garrigue, D ; Bouhours, G ; Dupont, H ; Bouzat, P ; Bardon, J & al , Time to source control and outcome in community-acquired intra-abdominal infections: The multicentre observational PERICOM study., Eur J Anaesthesiol, 2022, 5 - Pinson, J ; Tuech, JJ ; Ouaissi, M ; Mathonnet, M ; Mauvais, F ; Houivet, E & al , Role of protective stoma after primary anastomosis for generalized peritonitis due to perforated diverticulitis-DIVERTI 2 (a prospective multicenter randomized trial): rationale and design (nct04604730)., BMC Surg, 2022.

The unit welcomes students in Master 1, Master 2 and Thesis of Sciences.

Unit of research on clinical research in care, almost unique structure in France, bringing together medical and surgical researchers, multidisciplinary (surgeons of various horizons, anaesthetists), medical and non-medical researchers (medical science theses and by Clinical Research Associates). The subject of simplification of care is articulated with many themes and specialties and therefore makes this structure at the national level attractive for students of M1, M2 and science thesis who come from various backgrounds, from various regions in France. The international positioning is currently done through the list of publications (271) attached to the SSPC Unit since its creation.

We provide consulting services related to all our areas of expertise.

• University of Picardie Jules Verne (UPJV)

Société Française de Chirurgie Digestive

• Health and Nutrition
• New therapeutic approaches
• Prevention, well-being and the silver economy
• Medicine of the future: new health equipment and e-health