• Bioeconomy
  • Chemistry and Materials

Supramolecular Catalysis and Chemistry (CASU)

Research team


The Supramolecular Catalysis Team (CASU) is located at the Faculty of Science of Lens (Université d'Artois). It aims to develop catalytic systems and environmentally friendly chemical processes, with particular emphasis on the transformation of bio-based molecules and environmental remediation. This team is particularly interested in working on reactions of interest, such as the functionalization of vegetable oils (hydroformylation hydroxymethylation, hydroaminomethylation), the hydrogenation of unsaturated fatty acids or the oxidation and thinning of alcohols. Catalytic systems in many cases involve the use of native or modified cyclodextrins, polymerized or not. They can be used in biphasic systems consisting of an aqueous and an organic phase to improve the transfer of matter (phase transfer agents, self-assembled surfactants, colloids, emulsions). Cyclodextrins can also be used as dispersants and/or structuring agents (templates) for the preparation of more efficient heterogeneous or enzymatic catalysts. The CASU team is also involved in applied research projects in collaboration with other academic teams as well as with industry. It maintains and develops various partnerships with major industrial players in the field of chemistry.


  • Anne Ponchel
    Team manager


Université d'Artois, Faculté des Sciences Jean Perrin
623000 LENS



Effectif total : 25

Personnel de recherche : 15

Personnel d'appui à la recherche : 2



The CASU team’s research activities are in the field of sustainable chemistry, at the interface of two disciplines: catalysis and supramolecular chemistry. Its activities revolve around the following themes: i) molecular receptors for organometallic catalysis, ii) supramolecular self-assembly for catalysis, iii) metal nanoparticles stabilized by molecular receptors and iv) materials for heterogeneous catalysis. Composed of 15 lecturers-researchers, this team is multidisciplinary and brings together skills in Homogeneous Catalysis, Heterogeneous Catalysis, Colloidal Catalysis, Supramolecular Chemistry, Organic Synthesis, Preparation and Characterization of Catalytic and Nanomaterials.

Example(s) of projects

• As part of the "Investments for the Future" programme, the CASU team’s expertise in glycochemistry and lipochemistry enabled it to integrate two Energy Transition Institutes (IFMAS and PIVERT). 6 patents published between 2016 and 2019. 🡭
• Participation in the CPER Project 2021-2027 BiHauts Eco de France "Les bioressources végétales et microbiennes et l'innovation technologique au service de la Bioéconomie, dans les Hauts-de-France". Co-supported by A2U/UPJV and I-Site ULNE/ UMRt BioEcoAgro BEA. Sébastien Tilloy (U. Artois, UCCS, CASU) is co-coordinator of the Workpackage WP4 "Innovative eco-processes for intensifying the transformation and production of bio-based molecules".
• Participation in the CPER project 2021-2027 ECRIN "Environnement Climat – Recherche et INnovation". Co-supported by the A2U/ULCO site and the I-Site ULNE site. Anne Ponchel (U. Artois, UCCS, CASU) is co-coordinator of Atelier AT3 "Materials and Environmental Remediation Processes".
• Participation in the ANR Programme 2020-2023 Doctoral Contracts in Artificial Intelligence - Edition 2020 - VIVAH Towards human artificial intelligence "Determination of association constants Cyclodextrins/Guests by artificial intelligence for applications in catalysis" 🡭

Example(s) of publications

• Hydroformylation of alkenes in a planetary ball mill: from additive-controlled reactivity to supramolecular control of regioselectivity, K. Cousin, S. Menuel, E. Monflier, F. Hapiot, Angew. Chem. Int. Ed. 2017, 56, 10564-10568 - doi: 10.1002/anie.201705467
• Cyclodextrin-assisted low-metal Ni-Pd/Al2O3 bimetallic catalysts for the direct amination of aliphatic alcohols, A. Tomer, B. T. Kusema, J-F. Paul, C. Przybylski, E. Monflier, M. Pera-Titus, A. Ponchel, J Catal 2018, 368, 172-189 - doi: 10.1016/j.jcat.2018.10.002
• Confinement of Candida Antarctica Lipase B in a Multifunctional Cyclodextrin-Derived Silicified Hydrogel and its Application as Enzymatic Nanoreactor, C. Decarpigny, R. Bleta, A. Ponchel, E. Monflier, ACS Applied Bio Materials 2019, 2, 5568-5581 - doi: 10.1021/acsabm.9b00646
• Anionic Amphiphilic Cyclodextrins bearing Oleic Grafts for the Stabilization of Ruthenium Nanoparticles Efficient in Aqueous Catalytic Hydrogenation, A. Cocq, B. Léger; S. Noel; H. Bricout; F. Pilard; S. Tilloy; E. Monflier, ChemCatChem 2020, 12, 1013-1018 - doi: 10.1002/cctc.201901837
• Hydrohydroxymethylation of Ethyl Ricinoleate and Castor Oil, C. Becquet, F. Berche, H. Bricout, E. Monflier, S. Tilloy, ACS Sustain Chem Eng., 2021, 9, 9444-9454 - doi: 10.1021/acssuschemeng.1c02924

All publications can be found here : ici

Collaborations/Partners/Scientific clients

• Université du Littoral Côte d'Opale (Dunkerque);
• Université de Picardie Jules Verne (Amiens);
• Université de Lille (Villeneuve d'Ascq) ;
• IRCELYON - Université Lyon 1 ( Villeurbanne);
• Université de Poitiers (Poitiers);
• Université de Rennes 1 (Rennes);
• Université de Technologie de Compiègne (Compiègne);
• Sorbone Universités (Paris)

• University of Palermo, Palermo (Italy);
• Vilnius University, Vilnius (Lithuania) ;
• Institute of Chemical Technology, Mumbai (India);
• Cape Town University, Cape Town (South Africa);
• Stellenbosch University, Stellenbosch (South Africa);
• Queen Mary University of London, London (United Kingdom);
• Cardiff University, Cardiff (United Kingdom);
• Dortmund University, Dortmund (Germany).

Services offers

Applications sectors

  • Science / Research

Services provided

CHNS Elemental Analysis, NMR Analysis (1H, 13C, 15N, 31P), SEM Analysis, CPG, GC-MS and HPLC Analysis, FTIR Analysis, UV-Vis, Thermal Analysis (ATG/DSC), DLS Analysis - Zeasizer, H2-TPR Analysis, CO Chimisorption, Specific Area Measurement - BET Analysis - Pore Size and Volume, Organic Synthesis, Synthesis of mesoporous materials and catalysts, Chemical analysis (glycochemistry, oleochemicals), Analytical studies of traces of impurities, Quality control.

Consulting services

We provide consulting services on all our skills


Affiliated institutions / organisations

Unit(s) of attachment


Doctoral schools

Competitive cluster

Regional strategic areas of activity

  • Bioeconomy
    • Biobased chemistry
    • Biobased materials
    • Processes applied to the bioeconomy
  • Chemistry and Materials
    • Green chemistry
    • Industrial processes engineering, efficient processes
    • Organic chemistry
    • Textiles, composites, materials